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Give a man a bunch of any drug that suppresses Testosterone production to nearly zero and you will see a subsequent spike in neurotoxicity and cardiotoxicity, first steroid cycle for cutting. Creating a therapeutic amount of Estradiol in your body is mediated through Testosterone aromatizing into Estrogen. While there are synthetic steroids that have proven to act on Estrogen receptors, or aromatize into Estrogen themselves, they have inherent flaws that cannot match the bioidentical androgen our body modulates in all aspects with far greater ease. Dianabol aromatizes into 17α-methylestradiol and is inherently hepatotoxic. Equipoise (Boldenone) is a poor substrate for aromatase and is incredibly kidney toxic relative to Testosterone.
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